Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)
Conditions
Interventions
E:Respectively inhale hydrogen and oxygen, air, and nitrogen and oxygen in order
F:Respectively inhale hydrogen oxygen, nitrogen oxygen, and air in order
A:Respectively inhale air, nitrogen oxygen, and hydrogen oxygen in order
B:Respectively inhale air, hydrogen oxygen, and nitrogen oxygen in order
C:Respectively inhale nitrogen oxygen, air, and hydrogen oxygen in order
D:Respectively inhale nitrogen oxygen, hydrogen oxygen, and air in order
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Pulmonary function test within 6 months, in line with the GOLD diagnostic criteria for chronic obstructive pulmonary disease: FEV1/FVC<0.7 after inhalation of bronchodilators 2. The main diagnosis of admission is "chronic obstructive pulmonary disease with acute exacerbation"
Exclusion criteria
Exclusion criteria: 1. Left heart failure; 2. Unstable angina; 3. Myocardial infarction; 4. Lung cancer; 5. Bronchiectasis; 6. Tuberculosis; 7. Thoracic deformity; 8. Neuromuscular diseases; 9. Artificial airway; 10. Need mechanical ventilation; 11. Judging by other researchers that the six-minute walk test cannot be completed
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Six minutes walking distance; | — |
Secondary
| Measure | Time frame |
|---|---|
| Respiratory Mechanics Index;lung function;Modified Borg Score;Rating of Perceived Exertion; | — |
Countries
China
Contacts
Public ContactZheng Zeguang
The First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed