Space-occupying lung lesions
Conditions
Interventions
Trial group (esketamine group):Esketamine combined with dexmedetomidine for sedation and analgesia
Control group(Sufentanil group):Sufentanil combined with dexmedetomidine for sedation and analgesia
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients undergoing microwave ablation for elective lung tumor. ASA Grade ?-?. Age =18 years old, =80 years old. BMI:18-28 kg/m. Obtain informed consent from patients and sign informed consent
Exclusion criteria
Exclusion criteria: Patients with contraindications of the related anesthetic drugs in this study. Patients with severe liver and kidney function impairment before operation. Patients with conscious disorder, cognitive dysfunction and mental system disease. Patients who take sedative and analgesic drugs for a long time. Patients with severe hypertension (SAP =180mmHg, or DAP =110mmHg)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative respiratory parameters; | — |
Secondary
| Measure | Time frame |
|---|---|
| Calming effect (Ramsay score);Analgesic effect (VAS score);Total amount of remedial sedative and analgesic;Respiratory depression; | — |
Countries
China
Contacts
Public ContactYanhua Chen
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed