laparoscopic total hysterectomy
Conditions
Interventions
Esketamine Group:Anesthesia was induced with Esketamine,0.5mg/kg, propofol, 1-2 mg/kg
and then rocuronium, 0.6-0.9 mg/kg, to facilitate the insertion of a tracheal tube.
Anesthesia was maintained with Esketamine 0.5mg/kg /hour, and propofol, 4-9 mg/kg/hour. The infusion rate was titra
Opioid Group:Anesthesia was induced with sufentanil ,0.2-0.4µg /kg, propofol, 1-2 mg/kg
and then rocuronium, 0.9 mg/kg, to facilitate the insertion of a tracheal tube.
Anesthesia was maintained with remifentanil, 10-20 µg/kg/h, and propofol, 4-9 mg/kg/hour. The infusion rate was titrate
Sponsors
Changzhi People's Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1 Patients who signed an informed consent form 2 Patients undergoing elective laparoscopic total hysterectomy 3 ASAI - II 4 patients who were aged 20 to 70 years 5 BMI:20-28
Exclusion criteria
Exclusion criteria: 1 Patients with preoperative psychological disorders or a history of taking antidepressants 2 Patients who are allergic to narcotic drugs, cerebrovascular diseases, cardiovascular diseases with clinical symptoms, respiratory failure, severe obstructive ventilation dysfunction, and severe liver and kidney dysfunction 3 anaemia (Hb < 90g/L) 4 Patients undergoing elective laparoscopic total hysterectomy plus double adnexal resection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR-40;HADS-A/HADS-D;BDNF;5-HT; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS;shivering;PONV; | — |
Countries
China
Contacts
Public ContactWang Guoping
Changzhi People's Hospital
Outcome results
None listed