Lung space-occupying
Conditions
Interventions
Experimental group (bupivacaine liposome group):Paravertebral nerve block with liposomal bupivacaine
Control group (ropivacaine group):Paravertebral nerve block with ropivacaine
Sponsors
The First Affiliated Hospital of Guangxi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Age =18 years, =75 years, gender is not limited (2) The surgical procedure was a single-port thoracoscopic partial lung resection (3) The duration of the operation will not exceed 4 hours (4) BMI: 18-28kg/m2 (5) ASA classification I-III (6) Obtain informed consent from the patient and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Contraindications to nerve block: infection at the puncture site, allergy to local anesthetics, coagulation disorders (2) Hepatic and renal insufficiency (3) Preoperative use of analgesic drugs (4) A history of chronic pain or opioid abuse (5) Mental illness (6) Pregnant and lactating women (7) Patients who refuse to participate (8) Others who are not suitable for clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analog Scale (VAS) scores; | — |
Secondary
| Measure | Time frame |
|---|---|
| Numerical Rating Score;sufentanil dosage;Number of PCA self-controls and total amount of medication administered;Remedial analgesic medication duration and dosage; | — |
Countries
China
Contacts
Public ContactYanhua Chen
The First Affiliated Hospital of Guangxi Medical University
Outcome results
None listed