Acute pancreatitis
Conditions
Interventions
Saccharomyces boulardii group:Saccharomyces boulardii, orally, 2 sachets BID.
Routine therapy group:Routine therapy group
Sponsors
The First Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Diagnosis of acute pancreatitis; (2) SIRS score = 2 points (3) Within 72 hours of acute pancreatitis; (4) Be aged 18-75; 5. Be willing to follow the research procedure and sign the informed consent form
Exclusion criteria
Exclusion criteria: (1) Multiple organ failure (respiratory failure, circulatory failure, renal failure and intestinal failure) within 72 hours of onset; (2) Application of probiotics in the past 1 month; (3) Have metastatic malignant tumors, autoimmune diseases (such as systemic lupus erythematosus, autoimmune pancreatitis, giant cell arteritis, rheumatoid arthritis) or chronic infectious diseases (including human immunodeficiency virus or tuberculosis); (4) pregnant and lactating women; (5) Gastrointestinal fistula, gastrointestinal obstruction and other serious gastrointestinal lesions; Patients with central venous catheterization; (6) Pancreatitis after endoscopic retrograde cholangiopancreatography and chronic pancreatitis; biliary pancreatitis with acute purulent cholangitis; 7. Hypersensitivity to Saccharomyces boulardii.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| SIRS;WBC; | — |
Secondary
| Measure | Time frame |
|---|---|
| procalcitonin;Indicators of bowel function: improvement in abdominal pain, bloating, diarrhoea, vomiting, and bowel sounds, and resumption of voluntary bowel movements; C-reactive protein;neutrophil %; | — |
Countries
China
Contacts
Public ContactZhu Yin
The First Affiliated Hospital of Nanchang University
Outcome results
None listed