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Effect of transcutaneous auricular vagus nerve stimulation on postoperative gastrointestinal dysfunction in patients undergoing laparoscopic radical resection of colorectal cancer - a single-center, randomized, double-blind, controlled trial

Effect of transcutaneous auricular vagus nerve stimulation on postoperative gastrointestinal dysfunction in patients undergoing laparoscopic radical resection of colorectal cancer - a single-center, randomized, double-blind, controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075602
Enrollment
Unknown
Registered
2023-09-10
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PostoPerative gastrointestinal dysfunction

Interventions

Test group:Stimulator treatment site placed in the ear nail boat area (set at a frequency of 25Hz, 200 µs pulse width),Each patient was treated once at 30 minutes, stimulation once a day for three day

Sponsors

The Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age: =18 years old 2. Elective colorectal cancer surgery under general anesthesia 3.ASA is graded from I to III 4. Subjects voluntarily signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Refuse to sign the test consent 2. Have neuropsychiatric disorders and a history of neurological or psychiatric disorders 3. Skin damage, redness, infection, etc. at the site of the intended irritation 4. Visual and hearing impairment and difficulty in communication 5. Severe cardiovascular and cerebrovascular diseases, liver and kidney dysfunction (such as severe hepatitis, kidney failure) 6. There were tinnitus, sinus bradycardia and hoarseness before operation 7. Have asthma symptoms or history of asthma 8.History of previous colorectal surgery 9. Acute intestinal obstruction, intestinal perforation and other emergencies

Design outcomes

Primary

MeasureTime frame
The patient reported the time of first exhaust after operation;

Secondary

MeasureTime frame
NRS pain score ;15-item Quality of Recovery Score (QOR15 scale) ;Incidence of postoperative gastrointestinal dysfunction;Incidence of postoperative nausea and vomiting;Incidence of postoperative delirium;Time to first feces;Time to first oral feeding;Time to first leaving bed ;

Countries

China

Contacts

Public ContactCao Jun Li

Xuzhou Medical University/ The Affiliated Hospital of Xuzhou Medical University

caojl0310@aliyun.com+86 151 6216 0809

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026