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Multimodal ultrasound assessment of rheumatoid disease activity and cardiovascular risk

Multimodal ultrasound assessment of rheumatoid disease activity and cardiovascular risk

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300075591
Enrollment
Unknown
Registered
2023-09-08
Start date
2023-09-12
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rheumatoid arthritis

Interventions

Rheumatoid Arthritis Relief Group (Rheumatoid activity classification, DAS-28 score 5.1):None
Normal group:None

Sponsors

Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Normal volunteers ? Age = 18 years; ? Voluntary participation in this study. Rheumatoid arthritis patients ? RA diagnosis in accordance with the relevant criteria established by the American College of Rheumatology in 1987. ? No clear cardiovascular disease. ? Can cooperate to complete the examination.

Exclusion criteria

Exclusion criteria: Normal volunteers ? People with mental abnormality who cannot cooperate; ? Those with liver disease or abnormal liver function; ? Those with autoimmune disease or cardiovascular disease. ? Those who are receiving medication that affects vascular function. Rheumatoid patients ? Significant cardiac arrhythmia; ? Presence of a clear history of cardiovascular disease. ? Combined with other autoimmune diseases; ? Those with mental abnormality who cannot cooperate

Design outcomes

Primary

MeasureTime frame
Carotid artery intima-media thickness;Carotid artery intravascular diameter;Modulus of elasticity values of the superficial wall shear wave of the common carotid artery;Common carotid artery deep wall shear wave modulus of elasticity values;Common carotid artery superficial wall shear wave frequency dispersion value;Common carotid artery deep wall shear wave frequency dispersion values;

Secondary

MeasureTime frame
age;blood sedimentation;C-reactive protein;Rheumatoid arthritis-related specific antibodies;Arterial pressure Volume lndex;Arterial Velocity pulse Index;pulse wave velocity;Total Cholesterol;HDL Cholesterol;Systolic Blood Pressure;

Countries

China

Contacts

Public ContactLin Jin

Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine

jinlin205@163.com+86 135 6466 0847

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026