Lupus nephritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age 0-18 years old; (2) meet the diagnostic criteria of the 2009 American Rheumatology Association SLE; (3) Comply with the 2012 EULAR/ERA-EDTA guidelines.
Exclusion criteria
Exclusion criteria: (1) Children who have not been seen for the first time in our hospital; (2) Immunosuppressants have been regularly used for 6 months before admission; (3) Incomplete clinical data; (4) Duration of medication= 6 months; (5) Patients with primary kidney disease or other types of secondary kidney disease; (6) Combined with other immune diseases such as dermatomyositis and vasculitis; (7) Those who are allergic or intolerant to immunosuppressants such as tacrolimus, mycophenolate mofetil, cyclosporine or hormones.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Renal remission; | — |
Secondary
| Measure | Time frame |
|---|---|
| Relapse after induction of remission;24-hour urine protein;Urine albumin creatinine ratio;haemoglobin;white blood cell;platelet;albumin;cholesterol;Serum creatinine;Urea nitrogen;ESR ;Low C3;Low C4;Autoantibody;Urine routine;Microscopic examination of urine sediment; | — |
Countries
China
Contacts
Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology