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Analysis of short-term efficacy and long-term prognosis of lupus nephritis in children with different induction therapies

Analysis of short-term efficacy and long-term prognosis of lupus nephritis in children with different induction therapies

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300075587
Enrollment
Unknown
Registered
2023-09-08
Start date
2023-09-10
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lupus nephritis

Interventions

Case group:None

Sponsors

Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 18 Years

Inclusion criteria

Inclusion criteria: (1) Age 0-18 years old; (2) meet the diagnostic criteria of the 2009 American Rheumatology Association SLE; (3) Comply with the 2012 EULAR/ERA-EDTA guidelines.

Exclusion criteria

Exclusion criteria: (1) Children who have not been seen for the first time in our hospital; (2) Immunosuppressants have been regularly used for 6 months before admission; (3) Incomplete clinical data; (4) Duration of medication= 6 months; (5) Patients with primary kidney disease or other types of secondary kidney disease; (6) Combined with other immune diseases such as dermatomyositis and vasculitis; (7) Those who are allergic or intolerant to immunosuppressants such as tacrolimus, mycophenolate mofetil, cyclosporine or hormones.

Design outcomes

Primary

MeasureTime frame
Renal remission;

Secondary

MeasureTime frame
Relapse after induction of remission;24-hour urine protein;Urine albumin creatinine ratio;haemoglobin;white blood cell;platelet;albumin;cholesterol;Serum creatinine;Urea nitrogen;ESR ;Low C3;Low C4;Autoantibody;Urine routine;Microscopic examination of urine sediment;

Countries

China

Contacts

Public ContactZhou Jianhua

Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology

jhzhou@tjh.tjmu.tdu.cn+86 133 6726 6559

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026