lumbar degenerative disease
Conditions
Interventions
Experimental Group :Intervertebral fusion using allogeneic bone fusion cages
Control Group :Intervertebral fusion using PEEK material fusion cage
Sponsors
Department of Orthopedics, the First Affiliated Hospital of Army Military Medical University
Eligibility
Sex/Gender
All
Age
30 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Accept random selection of different intervertebral fusion cages in different intervertebral spaces, voluntarily participate and sign an informed consent form 2) Age 30-80 years old 3) Suffering from degenerative diseases such as lumbar disc herniation, lumbar spinal stenosis, and lumbar spondylolisthesis 4) Surgical indications for lumbar dual segment fusion surgery 5) Good understanding and compliance, able to communicate well with researchers and comply with the entire experimental requirements
Exclusion criteria
Exclusion criteria: 1)Active infection throughout the body 2) Obvious local inflammation 3) Fever or abnormal blood count 4) Suffering from mental illness 5) Any potential situation that may affect the effectiveness of fusion cage implantation, such as malignant tumors, congenital malformations, surgical site fractures, other underlying diseases, etc. 6) Any deformity that affects the process of bone shaping, including but not limited to severe osteoporosis, bone resorption, bone loss, and other metabolic disorders that affect the spine 7) Individuals who are prone to allergies or have abnormal physical conditions 8) Patients who do not have indications for fusion surgery or only require single segment fusion surgery 9) Insufficient tissue coverage of the patient's surgical site 10) Those with poor compliance who cannot be followed up on time 11) Patients participating in other clinical trials 12) Other situations that researchers believe are not suitable for enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Surgical segmental fusion rate;Surgical segment intervertebral space height;Surgical segment intervertebral foramen height;Surgical segmental fusion cage settlement;Visual analog pain scores;Oswestry disability index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgical segment;operative time;Surgical blood loss;Postoperative hospitalization time; | — |
Countries
China
Contacts
Public ContactHou Tianyong
Department of Orthopedics, the First Affiliated Hospital of Army Military Medical University
Outcome results
None listed