stroke
Conditions
Interventions
intervation group:TMS on DLPC and M1
control group:TMS on M1
Sponsors
Department of Rehabilitation Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
14 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1: Voluntary participation, understanding and signed by the patient himself or his immediate family members signed the informed consent 2: clear history of stroke, and imaging findings (head CT or MRI) and clinical findings meet the diagnostic criteria for stroke 3: The first stroke occurred in a single cerebral hemisphere 4: The intracerebral hemorrhage patient had not undergone cranial surgery 5: Age 14- 80 years old, no gender preference 6: Unlimited course of disease 7: stable condition, vital signs are stable and is consciousness 8: Motor dysfunction: 3 5, and no oral sleep medication 10: The frequency, type, and intensity of physical, occupational, or behavioral therapy must be maintained for at least 1 month prior to enrollment 11: Commitment to follow the study procedures and cooperate with the whole process of the study 12: Able to adhere to and cooperate with research intervention
Exclusion criteria
Exclusion criteria: 1: with Parkinson's disease, peripheral neuropathy and other motor dysfunction, imaging diagnosis of central nervous system damage in addition to stroke, brain trauma 2: History of epilepsy, use of epileptic drugs 3: with severe cognitive, speech, vision, hearing or mental disorders that affect the examination and treatment 4: Known risk factors for TMS, such as pacemakers, intracranial metal implants, and skull defects 5: co-existing diseases, such as tumors and serious respiratory, heart, liver, kidney, endocrine and hematopoietic diseases, pose a significant risk that may affect the study results or seriously interfere with the conduct of the study 6: with family history of epilepsy, metal pacemakers in the body, metal implants in the brain, cochlear implants and so on are not suitable for TMS treatment 7: alcohol or drug abusers 8: pregnant, nursing, planning to become pregnant during the study, or women of childbearing age who were not using reliable contraception 9: Participants in other clinical trials that influence the evaluation of the results of this study 10: Unable to complete the basic course of treatment, may be poor compliance (i.e. can not adhere to the treatment) and difficult to follow up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| FMA of upper limbs;PSQI; | — |
Secondary
| Measure | Time frame |
|---|---|
| actigraphy monitoring;PSG;fNIRS;ADL;TMS evaluation; | — |
Countries
China
Contacts
Public ContactJia Jinxuan
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
Outcome results
None listed