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Dose-Response study of esketamine combined with propofol for hysteroscopy

Dose-Response study of esketamine combined with propofol for hysteroscopy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075564
Enrollment
Unknown
Registered
2023-09-08
Start date
2023-09-08
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intrauterine disease

Interventions

case series:Adjust the dosage of induced ketamine based on the success or failure of hysteroscopy examination (defined as cervical dilation and poor placement conditions of hysteroscopy or involuntary

Sponsors

Wenling Maternity and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Age 20-60 years old, ASA I-II, BMI 18-28 kg /m2, no contraindications for hysteroscopy.

Exclusion criteria

Exclusion criteria: Exclusion criteria are as follows :(1) the patient refused to participate; (2) Allergic to esketamine or propofol; (3) Patients at serious risk of hypertension, diabetes, hyperthyroidism, increased intraocular pressure or intracranial pressure; (4) Combined with cardiovascular and respiratory diseases; (5) recent use of opioids and non-steroidal anti-inflammatory drugs; (6) Have a history of mental illness or mental problems; (7) Congenital cervical duct or uterine malformation, serious uterine adhesion resulting in hysteroscopy is difficult to implement; (8)ASA classification ASA=?.

Design outcomes

Primary

MeasureTime frame
The number of successful and unsuccessful cases of patients with different doses of esketamine to prevent the occurrence of intraoperative body movement;

Secondary

MeasureTime frame
Hysteroscopy time;Anesthesia recovery time;Number of additional cases of propofol;The number of cases of artificial assisted breathing;hemodynamics;

Countries

China

Contacts

Public ContactJie Liu

Wenling Maternity and Child Health Care Hospita

845707601@qq.com+86 158 5763 0500

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026