quality of recovery
Conditions
Interventions
groupA:ciprofol 0.2-0.5mg/kg induction and 0.4-3 mg/kg/h maintenance
groupB:propofol1-2mg/kg induction and 4-12 mg/kg/h maintenance
Sponsors
The First Affiliated Hospital of Zhengzhou University
Eligibility
Sex/Gender
All
Age
65 Years to 84 Years
Inclusion criteria
Inclusion criteria: 1) Age > =65 years; 2) Physical status II-IV of the American Society of Anesthesiologists ; 3) Body mass index (BMI) 15-28 kg/m2; 4) Planned abdominal surgery under total intravenous anesthesia;
Exclusion criteria
Exclusion criteria: 1) known allergy to eggs, soy products, or test drugs (propofol, ciprofol, remifentanil, cis-atracurium, neostigmine, atropine); 2) History of central nervous system disease; 3) Patients with severe hypertension, diabetes mellitus or hepatic or renal dysfunction, heart failure; 4) Difficult airway; 5) significant respiratory circulatory dysfunction; 6) refusal to sign the informed consent form;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| quality of recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| injection pain;Consumption of cyclophenol or propofol during consciousness loss;Mean arterial pressure (MAP);Heart rate (HR);MMSE rating;Postoperative delirium assessment;Evaluation of the European Five Dimensional Health Scale;Autonomous breathing recovery time;Extubation time;PACU restlessness score;The incidence of remedial analgesia and remedial antiemesis; | — |
Countries
China
Contacts
Public ContactYuan Jingjing
The First Affiliated Hospital of Zhengzhou University
Outcome results
None listed