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Multicenter clinical research on targeted temperature management of high-grade aneurysmal subarachnoid hemorrhage

Multicenter clinical research on targeted temperature management of high-grade aneurysmal subarachnoid hemorrhage

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075540
Enrollment
Unknown
Registered
2023-09-07
Start date
2022-04-01
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Subarachnoid hemorrhage

Interventions

Experimental group:Targeted temperature management
Control group:Routine temperature control

Sponsors

Henan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Age 18-80; (2) Intracranial aneurysms confirmed by head computed tomography (CTA) or digital subtraction angiography (DSA); (3) No history of intracranial benign and malignant tumors; (4)Hunt-Hess class IV-V; (5) Stable vital signs after rescue or early treatment; (6) Receiving craniotomy clipping or vascular embolization treatment; (7) The patient's legal representative signs the informed consent form.

Exclusion criteria

Exclusion criteria: (1) Known allergy to medical devices; (2) Systemic inflammatory response syndrome or sepsis was diagnosed at enrollment; (3) Have a history of blood system diseases, bleeding constitution, and coagulation dysfunction; (4) Have undergone major surgery in the past three months or have a history of craniocerebral trauma, gastrointestinal bleeding, and urinary system bleeding; (5) Patients with advanced renal failure requiring dialysis; (6) Life expectancy< 6 months; (7) Pregnant and lactating patients (8) Patients who the investigator believes are not suitable to participate in this program for other reasons.

Design outcomes

Primary

MeasureTime frame
Good prognosis rate;

Secondary

MeasureTime frame
Incidence of complications;Mechanical ventilation time, ICU hospitalization time, ICU hospitalization expenses;

Countries

China

Contacts

Public ContactGuang Feng

Henan Provincial People's Hospital

fgwxh@163.com+86 189 0371 1799

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026