Rheumatoid arthritis
Conditions
Interventions
Control group:Tofacitinib
Low-dose astragalus group:Astragalus and Gui Zhi Wu Wu Tang with Tofacitib Combined with Low Dose Astragalus
Medium-dose astragalus group:Astragalus and Gui Zhi Wu Wu Tang with Tofacitib Combined with Medium Dose of Astragalus
High-dose astragalus group:Astragalus and Gui Zhi Wu Wu Tang with Tofacitib combined with high dose of Astragalus membranaceus
Sponsors
Ethics Committee of Henan Provincial Hospital of Traditional Chinese Medicine (The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine)
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria of western medicine for rheumatoid arthritis; (2) Patients who meet the above TCM differentiation of qi and blood deficiency; (3) The patient is between 18 and 65 years old; (4) According to the DAS28-CRP score, the disease is in the active phase (DAS28-CRP>3.2); (5) Sign the consent form of the young people and have good compliance.
Exclusion criteria
Exclusion criteria: (1) Women preparing for pregnancy or lactation; (2) Patients with overlapping other rheumatisms such as systemic lupus erythematosus and Sjogren's syndrome; (3) Serious diseases of heart, cerebrovascular, digestive tract, liver, kidney, hematopoietic system; (4) Apply other therapeutic measures that affect the judgment of the efficacy of this observation plan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of the clinical efficacy of Western medicine;Evaluation of the efficacy of Chinese medicine symptoms;Evaluation of disease activity;security assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| visual analogue scale;C-reactive protein(CRP);erythrocyte sedimentation rate (ESR);rheumatoid factor;Disease Activity;Health assessment questionnaire;TCM Symptom Score; | — |
Countries
China
Contacts
Public ContactSongwei Li
Henan Provincial Hospital of Traditional Chinese Medicine (The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine)
Outcome results
None listed