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Effect of electroacupuncture "Tongmin Point" combined with heat moxibustion on knee osteoarthritis and influence on polyproteinase-4 and matrix metalloproteinase-3

Effect of electroacupuncture "Tongmin Point" combined with heat moxibustion on knee osteoarthritis and influence on polyproteinase-4 and matrix metalloproteinase-3

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075534
Enrollment
Unknown
Registered
2023-09-07
Start date
2020-12-31
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Knee osteoarthritis

Interventions

Experimental group:Electroacupuncture "pain-sensitive points" combined with heat-sensitive moxibustion + sodium vitrate knee joint cavity injection
Control group:Sodium vitrate knee joint cavity injection

Sponsors

Caidian District People's Hospital of Wuhan
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) After clinical examination, combined with imaging tests, and also meeting the the diagnosis of osteoarthritis of the knee; (2) patients who had not received acupuncture or moxibustion treatment in the last 2 months prior to inclusion in this study; and (3) patients who fully accepted this study method and who were willing to cooperate.

Exclusion criteria

Exclusion criteria: (1) those with combined diabetes, cardio-cerebral vascular disease, severe liver and kidney function impairment, malignant tumors and other diseases;(2) Pregnant and breastfeeding women; (3) Patients who, for various reasons, voluntarily abandon or are unable to cooperate with the treatment or observation; (4) Patients taking drugs outside the scope of the study, which affects the evaluation of the efficacy.

Design outcomes

Primary

MeasureTime frame
WOMAC Rating Scale;Content of ADAMTS-4 and MMPs-3 in serum;

Secondary

MeasureTime frame
The VAS rating scale;

Countries

China

Contacts

Public ContactMaozhen

Caidian District People's Hospital of Wuhan

517994770@qq.com+86 135 5425 9380

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026