tumor
Conditions
Interventions
S group:Inhaled sevoflurane
R group:Intravenous injection of remimazolam
Sponsors
The Fourth Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 90 Years
Inclusion criteria
Inclusion criteria: American Society of Anesthesia (ASA) physical status classification ?-?;The estimated operation time is more than 1 hour;Age =65 years;.No sedative or analgesic allergy history ; no history of allergic disease or mental illness ; not long-term use of sedative and analgesic drugs ; no opioid dependence or tolerance ; no bradycardia ; there was no obvious abnormality in heart, lung, liver and kidney function. They agreed to participate in this study and signed informed consent.
Exclusion criteria
Exclusion criteria: Patients or their family members refused to participate in the trial; patients who were allergic to benzodiazepines and any components of this product, myasthenia gravis, schizophrenia, severe depression; patients who planned to undergo a second operation during the same hospitalization; preoperative mini-mental state scale (MMSE) score = 23
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of daily delirium within 5 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| length of stay;cognitive function;pain score; | — |
Countries
China
Contacts
Public ContactHuaqin Liu
The Fourth Hospital of Hebei Medical University
Outcome results
None listed