Coronary heart disease
Conditions
Interventions
Experimental group:Xinyue capsule
Control group:placebo
Sponsors
The Affiliated Hospital of Changchun University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age 30~75 years old, gender unlimited; 2. In accordance with the diagnostic and Treatment Guidelines for Chronic Stable Angina Pectoris (2007 edition) of the Chinese Medical Association, the diagnostic criteria for stable angina pectoris are as follows: There is angina pectoris attack, but the degree, frequency, time and inducment of the attack do not change within a few weeks: ? There were dynamic changes in the ECG during chest pain attack, which were consistent with the ECG of myocardial ischemia, and the 24-hour dynamic ECG changes were consistent with the symptoms of ST; Coronary angiography or coronary CT=50% stenosis; ? Patients with asymptomatic or stable symptoms after ACS stabilization; ? microcirculatory angina pectoris; 3. Consistent with TCM Qi and Yin deficiency syndrome type; 4. Meet the FS14 fatigue scale score =3, and do not suffer from other diseases that can explain chronic fatigue symptoms; 5. Voluntarily sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Uncontrolled grade 3 hypertension (=180/100mmHg) or hypotension (< 90/60mmHg); 2. History of stroke (cerebral hemorrhage, subarachnoid hemorrhage, cerebral thrombosis, cerebral embolism and stroke with unknown type) or lower limb artery disease in the past 6 months; 3. History of pregnancy, preparation or suspected pregnancy, miscarriage, breastfeeding or post-delivery within the last 6 months. 4. Combined with episodic bronchial asthma or chronic obstructive pulmonary disease; 5. Severe allergy, known or likely to be allergic to the test drug or its components; 6. Known bleeding tendencies or bleeding disorders; 7. Complicated with severe hepatic and renal dysfunction (creatinine clearance =40ml/min or renal activity stage, serum transaminase =2× the upper limit of clinical reference value); 8. Excluding patients with heart failure, senile sarcopenia, tumor, anemia, hypothyroidism, myasthenia gravis, and psychiatric diseases; 9. The investigator believes that there may be other conditions affecting the clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue Scale (FS-14); | — |
Secondary
| Measure | Time frame |
|---|---|
| electrocardiogram;EQ5D scale; | — |
Countries
China
Contacts
Public ContactXiaoping Meng
The Affiliated Hospital of Changchun University of Traditional Chinese Medicine
Outcome results
None listed