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Comparision of postoperative analgesia of thoracic paravertebral block under thoracoscopy with different doses of Esketamine combined with ropivacaine in thoracic surgery

Comparision of postoperative analgesia of thoracic paravertebral block under thoracoscopy with different doses of Esketamine combined with ropivacaine in thoracic surgery

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075510
Enrollment
Unknown
Registered
2023-09-07
Start date
2023-09-07
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic tumor

Interventions

S1 Group:20ml of 0.1mg/kg Esketamine+0.375% ropivacaine were injected into the thoracic 5 and 6 paravertebral spaces under the guidance of thoracoscopy
S2 Group:20ml of 0.2mg/kg Esketamine+0.375% ropivacaine were injected into the thoracic 5 and 6 paravertebral spaces under the guidance of thoracoscopy
S3 Group:20ml of 0.3mg/kg Esketamine+0.375% ropivacaine were injected into the thoracic 5 and 6 paravertebral spaces under the guidance of thoracoscopy

Sponsors

Ningbo Medical Center Li Huili hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients aged 20-75 years old, classified by the American Society of Anesthesiologists (ASA) as Grade I-II, without neurological or muscular disorders, spinal deformities, fractures, trauma, or surgical history, who agreed to participate in this study.

Exclusion criteria

Exclusion criteria: Allergies to ropivacaine and Esketamine, abnormal coagulation function, history of spinal deformities, fractures, injuries, or surgeries, history of thoracic aortic aneurysm, failure to cooperate or request withdrawal during the research process

Design outcomes

Secondary

MeasureTime frame
Duration of sensory blockade;Postoperative analgesia;Postoperative adverse reactions;

Primary

MeasureTime frame
Rest and exercise (deep breathing or coughing) NRS score and Ramsay sedation score;

Countries

China

Contacts

Public ContactLihong Hu

Ningbo Medical Center Li Huili hospital

hlh_2000@163.com+86 135 8658 4415

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026