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Effect of sevoflurane combined with remimazolam on general anesthesia during surgery

Effect of sevoflurane combined with remimazolam on general anesthesia during surgery

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075498
Enrollment
Unknown
Registered
2023-09-06
Start date
2023-09-06
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gynecological disease

Interventions

R0:Remimazolam 0 mg·kg-1·h-1
R1:Remimazolam 1mg·kg-1·h-1
R2:Remimazolam 1.5mg·kg-1·h-1
R3:Remimazolam 2.0mg·kg-1·h-1

Sponsors

Nanchong Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: ASAI-II class, age 20-45 years, body mass index (BMI) 18-30 kg/m2, no history of upper respiratory tract and pulmonary infections 2 weeks prior to surgery, no history of asthma, and estimated operative time within 2 hours.

Exclusion criteria

Exclusion criteria: patients with body mass index > 30 kg/m2; chronic alcohol and drug abusers; patients with abnormal cardiopulmonary function; patients with allergy to benzodiazepines; patients with myasthenia gravis, patients with family history of malignant hyperthermia.

Design outcomes

Primary

MeasureTime frame
MACBAR value of sevoflurane ;

Secondary

MeasureTime frame
heart rate;Mean arterial pressure;Bispectral index of EEG;

Countries

China

Contacts

Public ContactYan Huang

Nanchong Central Hospital

13990775755@163.com+86 139 9077 5755

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026