stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1: ? Meet the diagnostic criteria of cerebral infarction or cerebral hemorrhage 2: ? Hemiplegia of limbs left after cerebrovascular accident for the first time 3: ? Patients with grade ? to ? wrist flexion spasm (MAS) 4: ? The age ranges from 35 to 80 years 5: ? The onset of the disease was 3-18 months 6: ? Have the ability to understand commanding actions 7: ? The patient's vital signs were stable 8: (8) The dosage of spasmolysis drugs did not change during the treatment and follow-up period 9: ? Those who agree to sign the informed consent.
Exclusion criteria
Exclusion criteria: ? Previous motor dysfunction, such as rheumatoid arthritis, joint deformity, spinal cord injury and other diseases that have a direct impact on motor function 2: ? Prior botox, alcohol and phenol block therapy 3: (3) surgical orthopaedic wrist surgery before 4: ? At the same time with straightening wrist spasm ? grade ? 5: ? Patients with severe hypertension, whose blood pressure is still higher than 180/110mmHg after 1 week of regular treatment, atrial fibrillation, unstable angina pectoris, severe lung infection, severe cardiac and renal failure, and severe diabetes 6: ? Have a history of epilepsy 7: ? Severe mental disorders 8: ? Malignant tumor 9: ? Thrombosis of limb veins.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MAS; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment Scale, FMAS;visual analogue scale,VAS;Resting-state functional magnetic resonance imaging,rs-fMRI;the Barthelindex;Motor evoked potential,rMT;Swelling score; | — |
Countries
China
Contacts
Shanghai Xuhui District Central Hospital