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Study on the efficacy and mechanism of pairwise associative transcranial magnetic stimulation combined with hypothermic thermoplastic plate orthosis in patients with carpal flexor spasm after stroke

Study on the efficacy and mechanism of pairwise associative transcranial magnetic stimulation combined with hypothermic thermoplastic plate orthosis in patients with carpal flexor spasm after stroke

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075497
Enrollment
Unknown
Registered
2023-09-06
Start date
2022-01-18
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

treatment group:Paired associative stimulus and orthopedic
control group:orthopedic

Sponsors

Shanghai Xuhui District Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1: ? Meet the diagnostic criteria of cerebral infarction or cerebral hemorrhage 2: ? Hemiplegia of limbs left after cerebrovascular accident for the first time 3: ? Patients with grade ? to ? wrist flexion spasm (MAS) 4: ? The age ranges from 35 to 80 years 5: ? The onset of the disease was 3-18 months 6: ? Have the ability to understand commanding actions 7: ? The patient's vital signs were stable 8: (8) The dosage of spasmolysis drugs did not change during the treatment and follow-up period 9: ? Those who agree to sign the informed consent.

Exclusion criteria

Exclusion criteria: ? Previous motor dysfunction, such as rheumatoid arthritis, joint deformity, spinal cord injury and other diseases that have a direct impact on motor function 2: ? Prior botox, alcohol and phenol block therapy 3: (3) surgical orthopaedic wrist surgery before 4: ? At the same time with straightening wrist spasm ? grade ? 5: ? Patients with severe hypertension, whose blood pressure is still higher than 180/110mmHg after 1 week of regular treatment, atrial fibrillation, unstable angina pectoris, severe lung infection, severe cardiac and renal failure, and severe diabetes 6: ? Have a history of epilepsy 7: ? Severe mental disorders 8: ? Malignant tumor 9: ? Thrombosis of limb veins.

Design outcomes

Primary

MeasureTime frame
MAS;

Secondary

MeasureTime frame
Fugl-Meyer Assessment Scale, FMAS;visual analogue scale,VAS;Resting-state functional magnetic resonance imaging,rs-fMRI;the Barthelindex;Motor evoked potential,rMT;Swelling score;

Countries

China

Contacts

Public Contactgaiya li

Shanghai Xuhui District Central Hospital

625873123@qq.com+86 18 708 152 7474

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026