Long COVID-19 syndrome Fatigue
Conditions
Interventions
acupuncture group:acupuncture treatment
sham-acupuncture group:sham-acupuncture treatment
Healthy control group:None
Sponsors
The First People's Hospital of Zunyi
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for subjects of long COVID-19 syndrome: (1) Patients who meet the diagnostic criteria of Chinese and Western medicine and voluntarily participate in the trial and cooperate; (2) Right-handed; (3) Age 18-65 years old, with a course of disease of = 2 months; (4) No relevant traditional Chinese and western medicine treatment, sedative, hypnotic, Melatonin, antidepressant and other psychotropic drugs were taken in the past month; (5) Severe primary diseases such as heart, brain, kidney, and hematopoietic system, as well as mental illness; (6) Able to accurately understand the meaning of various scales and sign informed consent forms. (7) Not participating in other ongoing clinical studies. Inclusion criteria for healthy subjects: (1) Age 18-65 years old, right-handed; (2) No functional or organic diseases were found through physical examination; (3) Those who have not taken any medication for at least 15 days before entering the study and have not participated in other clinical studies; (4) I have signed an informed consent form and voluntarily participate in this study.
Exclusion criteria
Exclusion criteria: Exclusion criteria for subjects with long COVID-19 syndrome: (1) Symptoms that can be explained by other diseases; (2) Acupuncture and moxibustion operators cannot be performed due to a history of faintness/intolerance to acupuncture, or injury of the operation site; (3) Complicated with serious cardiovascular, cerebrovascular, liver, kidney, stomach, hematopoietic and Nervous system disease; (4) Pregnant or lactating women and those with pregnancy plans in the past 3 months; (5) Individuals with combined aphasia or severe visual, auditory, or cognitive impairment; (6) Patients with severe depression and anxiety (Beck Depression Inventory = 16 points); (7) There are metal implants in the body, contraindications for fMRI detection or Claustrophobia. Note: Anyone who meets any of the above 7 criteria is excluded. Exclusion criteria for healthy subjects: (1) History of cerebrovascular disease, brain parenchyma disease and Head injury; (2) There are metal implants in the body; (3) Pregnant or lactating women and those with pregnancy plans in the past 3 months; (4) Those who work at night or have irregular sleep patterns and are unable or unwilling to stop this pattern; (5) Magnetic resonance imaging shows clear organic lesions in the brain or severe asymmetry in the anatomical structure of the head; Note: Any one of the above 5 criteria is excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Checklist for individual strength(CIS);FMRI evaluation indicators;MRS evaluation indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Somatic and psychological health report,SPHERE;Short form-36 health survey,SF-36; | — |
Countries
China
Contacts
Public ContactHongjiao Jin
The First People's Hospital of Zunyi
Outcome results
None listed