spesis
Conditions
Interventions
Sponsors
the National Natural Science Foundation of China-Regional Innovation and Development Joint Fund
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) Admission to ICU; 2) 18 years old< age < 65 years old; 3) Diagnosis of sepsis based on history, clinical manifestations, laboratory tests and imaging tests (consistent with The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3), 2016); 4) Patients with endotracheal intubation
Exclusion criteria
Exclusion criteria: 1) Pregnant and lactating women; 2) The patient or his family does not agree; 3) Patients who are transferred, discharged or die within 7 days of admission to the ICU; 4) Incomplete clinical data; 5) Application of immunomodulatory drugs (such as thymus peptide, glucocorticoids, etc.) within 7 days of admission to the ICU; 6) There are autoimmune diseases, and long-term immunomodulatory drugs are used
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory factors;Blood cells (ILCs, MDSCs);16srRNA sequencing;Non targeted metabolomics; | — |
Countries
China
Contacts
Public ContactKaijiang Yu
he First Affiliated Hospital of Harbin Medical University, Harbin Medical University
Outcome results
None listed