Membranous nephropathy
Conditions
Interventions
Western medicine section (Basic therapy combined with hormone and immunosuppressive agents):NA
Chinese and western medicine group (Western medicine group treatment on the basis of Qidi Gushen capsule):NA
Western medicine section (Primary therapy):NA
Chinese medicine section (Basic treatment combined Qidi Gushen capsule):NA
Sponsors
The First Affiliated Hospital of Shaanxi University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Those who meet the Western diagnostic criteria for primary membranous nephropathy (IMN); 2.Those who meet the diagnostic criteria of spleen, kidney, Qi and Yin deficiency syndrome of traditional Chinese medicine; 3.Age, gender is not limited; 4.Serum creatinine level is less than 265µmol/L; 5.24 hours urinary protein quantity is greater than or equal to 1g/d; 6.Voluntary signing of informed consent for clinical research.
Exclusion criteria
Exclusion criteria: 1.Confirmed by hepatitis B, systemic lupus erythematosus, tumor, diabetic nephropathy, drug damage and other factors secondary; 2.Patients with acute central nervous system disease, severe gastrointestinal disease, HIV infection history, psychiatric history; 3.Combined with serious diseases and dysfunction of other organs; 4.Patients with water and sodium retention, hyperkalemia, metabolic acidosis, and severe anemia that cannot be corrected by drugs are considered for renal replacement therapy; 5.Take other proprietary Chinese medicines related to this study, such as "Bailing capsule, Shenwu Yishen tablet, Yishenhuazhuo granules" and other proprietary Chinese medicines; 6.Pregnant or lactating women or investigators undergoing other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24h urinary protein quantification;Blood albumin;triglyceride;Total cholesterol;Antiphospholipase A2 receptor antibody titer; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urea nitrogen;Serum creatinine;Uric acid;Glomerular filtration rate; | — |
Countries
China
Contacts
Public ContactLi Xiaohui
The First Affiliated Hospital of Shaanxi University of Chinese Medicine
Outcome results
None listed