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A prospective, randomized, double-blind study on the effect of Weijing decoction on the risk of long-term acute exacerbation of bronchiectasis patients with Pseudomonas aeruginosa colonization (syndrome of phlegm-heat accumulation in the lung)

A prospective, randomized, double-blind study on the effect of Weijing decoction on the risk of long-term acute exacerbation of bronchiectasis patients with Pseudomonas aeruginosa colonization (syndrome of phlegm-heat accumulation in the lung)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075448
Enrollment
Unknown
Registered
2023-09-05
Start date
2023-10-01
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchiectasis

Interventions

Weijing decoction group:Weijing decoction granule preparation was given one bag at a time, three times a day, and the course of treatment was 12 weeks.
blank control group:The patients were given the granule preparation with the same appearance, smell, taste and weight of Weijing decoction, one bag at a time, taken with water, three times a day, and

Sponsors

Traditional Chinese Medicine Hospital Affiliated to Southwest Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age =18 years old and =75 years old, both sexes; 2. Meet the diagnostic criteria of bronchiectasis and the syndrome of phlegm-heat accumulation in the lung, in a stable state of bronchiectasis; 3. At least 2 cultures of Pseudomonas aeruginosa from sputum or bronchoalveolar lavage during stable bronchiectasis within 2 years before enrollment (PA colonization); 4. Voluntarily participate and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Complicated with Mycobacterium tuberculosis infection and a history of life-threatening massive hemoptysis; 2. Pregnant or lactating women; 3. Hepatic and renal insufficiency; 4. combined with malignant tumors; 5. Poor compliance.

Design outcomes

Primary

MeasureTime frame
TCM clinical symptom score;Modified British Medical Research Council dyspnea Scale;Proportion and frequency of acute exacerbations in one year;

Countries

China

Contacts

Public ContactAo Suhua

The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University

463787216@qq.com+86 13550898592

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026