breast cancer
Conditions
Interventions
Control group:No intervention
High volume group:Modified intercostal nerve block was performed with 40ml 0.33% ropivacaine
Low volume group:Modified intercostal nerve block was performed with 20ml 0.33% ropivacaine
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective breast cancer surgery 2. Aged 18-65 years old 3.ASA ?-? 4. Weight 50-80kg
Exclusion criteria
Exclusion criteria: 1. Contraindications to nerve block, including but not limited to allergy to anesthetics, coagulopathy, and injection site infection (2) opioid use for more than 4 weeks or preoperative chronic pain for more than 3 months 3. Have severe comorbidities, including but not limited to renal insufficiency (creatinine >442moL/L or need for renal replacement therapy), hepatic insufficiency and heart failure, or ASA grade =IV 4.BMI>35kg/m² or <15 kg/m2 5. Accompanied by inability to accurately participate in the evaluation of postoperative analgesia 6. The anatomy of ultrasound scan was difficult, and nerve block surgery could not be performed 7. No informed consent was obtained
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS scores at rest and during activity at 12h after surgery;Remifentanil usage; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS scores at rest and during activity after postoperative recovery;NRS scores at rest and during activity at 6h after surgery;NRS scores at rest and during activity at 24h after surgery;NRS scores at rest and during activity at 48h after surgery;NRS scores at rest and during activity at 72h after surgery;Intraoperative hemodynamic fluctuations;The incidence of postoperative delirium;Postoperative anxiety and depression;Postoperative sleep quality; | — |
Countries
China
Contacts
Public ContactXu Guanghong
the First Affiliated Hospital of Anhui Medical University, 218 Jixi Road, Hefei, Anhui 230022, China
Outcome results
None listed