osteoporotic vertebral compression fracture
Conditions
Interventions
TAX group:In TXA group, 20min and intravenous drip of 100ml saline + TXA1.0g were given before operation.
control group:Intravenous drip with the same dose of normal saline
Sponsors
Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: (1) the age is between 60 and 80 years old; (2) the fracture can be diagnosed definitely according to the relevant medical history, symptoms, signs and related auxiliary examination; (3) the mode of operation must be percutaneous transluminal vertebroplasty; (4) the body mass index (BMI= weight / height ²) is between 18.5-24Kg/ (m) ²; (5) the ASA score is grade I-III.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1 allergic to tranexamic acid (TXA); 2 pathological fractures, old fractures or associated malignant tumors; 3 having suffered from thrombotic diseases (deep venous thrombosis, pulmonary embolism, etc.), disseminated intravascular coagulation, abnormal coagulation function, etc.; 4 complicated with severe respiratory, digestive, blood system diseases or fractures in other parts; 5 other anticoagulants or procoagulant drugs are being used at present.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recessive blood loss after operation;Thrombosis of lower extremities and lungs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Restoration height of vertebral body;Blood routine;Blood coagulation index;Incidence of anemia; | — |
Countries
China
Contacts
Public ContactZhu Jieyang
Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China
Outcome results
None listed