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Evaluation of the efficacy of platelet-rich plasma injection combined with pulsed radiofrequency in the treatment of neuropathic pain in elderly patients: a randomized controlled study

Evaluation of the efficacy of platelet-rich plasma injection combined with pulsed radiofrequency in the treatment of neuropathic pain in elderly patients: a randomized controlled study

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075427
Enrollment
Unknown
Registered
2023-09-05
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elderly neuropathic pain

Interventions

Experimental group:In the experimental group, PRP2mL was injected through the puncture needle after the end of the RF pulse.
Control group:The control group was injected with analgesic solution (lidocaine 2ml+ Micobor 2ml+ debuzone 1ml+ normal saline 5ml) by puncture needle after pulsed RF therapy.

Sponsors

Department of Pain Management,West China Hospital,Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1) Patients aged =65 years old 2) patients diagnosed with various neuropathic pain 3) patients with poor pain control or inability to tolerate adverse drug reactions after standardized drug therapy 4) Patients voluntarily signed informed consent for this study 5) contraindications were excluded before surgery 6) pain visualanalog scale (VAS) score =4 points upon admission.

Exclusion criteria

Exclusion criteria: 1) Patients with drug allergy 2) patients with mental disorders and intellectual disabilities who cannot tolerate minimally invasive surgery 3) patients with severe cardiac, cerebral, renal and liver dysfunction 4) patients with abnormal coagulation function 5) patients with sepsis 6) patients with puncture site infection7) Non-steroidal anti-inflammatory analgesics were discontinued for less than 48h8) systemic corticosteroid therapy was discontinued for less than 2 weeks 9) Patients with hematopoietic or skeletal tumors 10) patients with pacemakers 11) pregnant or puerperal patients 12) patients who could not objectively describe symptoms or could not use VAS score 13) patients who could not complete the 3-month follow-up after treatment

Design outcomes

Primary

MeasureTime frame
VAS scores were performed before surgery, at 1, 4 and 12 weeks after surgery;BPI score on quality of life index ;Pittsburgh Sleep Quality Index Scale score ;

Secondary

MeasureTime frame
Medication treatment status;patient satisfaction;Economic indicators;Safety evaluation;

Countries

CHina

Contacts

Public ContactYe Ling

Department of Pain Management,West China Hospital,Sichuan University

zerodq_hx@163.com+86 189 8060 1894

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026