Clinical observation on the analgesic effect of different doses of esketamine on postoperative visceral pain in patients undergoing laparoscopic surgery

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300075421

Enrollment

Unknown

Registered

2023-09-05

Start date

2022-08-01

Completion date

Unknown

Last updated

2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group N:0.3mg/kg esketamine

Group P:0.5mg/kg esketamine

Group C:saline group

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.Patients scheduled for laparoscopic abdominal surgery under general anesthesia; 2.Age 18-65 years; 3.BMI of 18-30 kg/m2; 4.ASA physical status I or II; 5.Agree to participate in the trial and sign the consent form.

Exclusion criteria

Exclusion criteria: 1. Hyperthyroidism,uncontrolled hypertension or coronary heart disease;2.Chronic pain;3.Opioid drug abuse;4. Allergy to esketamine;5.neurological diseases, mental and psychological disorders;5.Significant liver and kidney function abnormalities;7.Conversion to open surgery, or refusal to participate in the study;8.The amount of bleeding during the operation is greater than 800ml.

Design outcomes

Primary

Measure	Time frame
visceral pain VAS score;	—

Secondary

Measure	Time frame
incision pain VAS score;referred pain VAS score;BCS Score;the time of respiratory restoration;the time of conscious restoration time;the time of extubation;adverse reaction;	—

Countries

China

Contacts

Public ContactXueke Du

The Second Affiliated Hospital of Guangxi Medical University

duxueke@gxmu.edu.cn+86 173 0771 1159

Outcome results