HIV-associated DLBCL
Conditions
Interventions
HIV-DLBCL group:None
HIV-negative DLBCL group:None
Health group:None
Sponsors
The Second Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria (except health group) : 1) Diffuse large B-cell lymphoma (experimental group and HIV-negative DLBCL group) or lymph node reactive hyperplasia (lymph node reactive hyperplasia group) was pathologically confirmed; 2) =18 years old; 3) Detailed clinical data such as age, sex, the first four items of blood transfusion and lactate dehydrogenase were registered in all enrolled cases; 4) Sign informed consent, fully understand and comply with the requirements of the research scheme, and have the intention to complete the study as planned. Inclusion criteria (health group) : 1) =18 years old; 2) Those who deny serious diseases, infectious diseases, chronic diseases and hereditary diseases, such as tumors, diabetes, hypertension, etc.; 3) Physical examination items include blood routine, liver and kidney function, abdominal color ultrasound, chest radiograph, and the results are normal; 4) The enrolled cases were all registered with detailed basic information, such as age, sex, etc. 5) Sign informed consent, fully understand and comply with the requirements of the research scheme, and have the intention to complete the study as planned.
Exclusion criteria
Exclusion criteria: 1) A history of other malignancies; 2) Severe cardiovascular and cerebrovascular diseases, coagulation, autoimmune and infectious diseases, etc.; 3) Pregnant and lactating women; 4) Any other condition in which the investigator considers the patient not eligible to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IL-1ß;CD4+ T cell subsets; | — |
Secondary
| Measure | Time frame |
|---|---|
| Th1, Th2, Th17, Treg cell content; | — |
Countries
China
Contacts
Public ContactZeping Zhou
The Second Affiliated Hospital of Kunming Medical University
Outcome results
None listed