intestinal ployps
Conditions
Interventions
Experimental group:2L polyethylene glycol (PEG) plus linaclotide
Control group:4L polyethylene glycol (PEG)
Sponsors
The First Affiliated Hospital, Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. age between 18 and 80 years; 2. presence of at least one colorectal polyp and scheduled for colonoscopy polypectomy; 3. ability to complete the entire procedure after providing written informed consent.
Exclusion criteria
Exclusion criteria: 1. severe gastrointestinal symptoms such as gastrointestinal obstruction, gastrointestinal perforation, acute bowel disease, or gastrointestinal bleeding; 2. recent use of anticoagulant drugs (such as aspirin and warfarin) within 7 days before the scheduled colonoscopy; 3. pregnancy; 4. recent use of linaclotide or other laxatives within the past seven days or known allergy to linaclotide; 5. previous colonoscopy within the past two weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Boston Bowel Preparation Scale (BBPS); | — |
Secondary
| Measure | Time frame |
|---|---|
| tolerability and safety of the different bowel preparation agents;complications and infection status after polypectomy.;The size and number of polyps removed; | — |
Countries
China
Contacts
Public ContactHuiying Zhao
The First Affiliated Hospital, Zhejiang University School of Medicine
Outcome results
None listed