Screening and validation of serum exosomal proteins and miRNA associated with postoperative delirium in elderly patients with hip frature

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2300075409

Enrollment

Unknown

Registered

2023-09-04

Start date

2023-10-01

Completion date

Unknown

Last updated

2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post operative delirium

Interventions

POD group:None

Non-POD group:None

Eligibility

Sex/Gender

All

Age

65 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1) Age = 65 years old; 2) Being able to communicate normally before operation; 3) Patients without history of mental illness or have suffered from mental illness but have recovered or have no clinical symptoms; 4) Patients without cerebrovascular accident sequelae and no history of cerebrovascular surgery; 5)Patients without history of drug (alcohol) addiction and abuse

Exclusion criteria

Exclusion criteria: 1) American Association of Anesthesiologists (ASA) Grade V; 2) Age < 65 years old; 3) Peripheral nerve block or intraspinal anesthesia failure was changed to endotracheal intubation or laryngeal mask general anesthesia; 4) Patients who were transferred to ICU and received ventilator treatment due to illness factors after operation

Design outcomes

Primary

Measure	Time frame
Serum exosomal proteins;Serum exosomal miRNA;	—

Countries

CHINA

Contacts

Public ContactLiyong Yuan

Ningbo No.6 Hospital

yuanl1973@yeah.net+86 180 6710 9033

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026