Hypertension
Conditions
Interventions
Hypertension with LVH:None
Hypertension validation group:None
Hypertension with LVH validation group:None
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:Control group inclusion criteria for hypertension: ? Patients diagnosed with primary hypertension without left ventricular hypertrophy. The diagnostic criteria for primary hypertension are as follows: average 24-hour blood pressure =130/80; clinic blood pressure =140/90; isolated systolic hypertension with systolic blood pressure =140 and diastolic blood pressure <90 mm Hg (1 mm Hg = 0.133 kPa); ? Age range of 35-75 years; ? Signed informed consent form. Inclusion criteria for hypertension with left ventricular hypertrophy group: ? Patients meeting the diagnostic criteria for primary hypertension with left ventricular hypertrophy. The diagnostic criteria for primary hypertension are as follows: average 24-hour blood pressure =130/80; clinic blood pressure =140/90; isolated systolic hypertension with systolic blood pressure =140 and diastolic blood pressure <90 mm Hg (1 mm Hg = 0.133 kPa); the diagnostic criteria for left ventricular hypertrophy are as follows: echocardiography shows left ventricular mass index (LVMI) =115 (males) or =95 g/m2 (females); ? Age range of 35-75 years; ? Signed informed consent form.
Exclusion criteria
Exclusion criteria: Exclusion criteria: ? Patients with secondary hypertension; ? Patients with primary or other secondary cardiomyopathies; ? Patients with malignant tumors, thyroid dysfunction, or severe liver and kidney dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| DNA methylation;receiver operating characteristic curve, ROC; | — |
Countries
China
Contacts
Public ContactYuqi Liu
chinese PLA General Hospital
Outcome results
None listed