Critical illness
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) All subjects are adults over 18 years old; (2) Subjects used nutritional preparations during ICU stay; (3) Subjects are expected to stay in ICU for more than 9 days; (4) All subjects or their family members are willing to participate in the test and sign the informed consent.
Exclusion criteria
Exclusion criteria: (1) The subjects have abnormal secretion of other hormones, such as thyroid hormone, parathyroid hormone, adrenotropic hormone, growth hormone, etc.; (2) patients with severe burn; (3) The subject is pregnant or lactating. (4) Patients with severe liver insufficiency, severe renal insufficiency and no hemofiltration; (5) patients with advanced malignant tumor and fluid deficiency; (6) Patients in shock, hemodynamic instability and still requiring high dose of norepinephrine 3 days after entry;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day mortality rate;Length of ICU stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Laboratory indicators serum total protein (TP), serum albumin (ALB), prealbumin (PA), C-reactive protein (CRP);Serum amino acid content reached the standard rate;Total length of stay; | — |
Countries
China
Contacts
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School