Helicobacter pylori infection
Conditions
Interventions
Sponsors
The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1)13C urea breath test or rapid urease test positive; (2) Aged 18-70 years old; (3) Agree to undergo gastroscopy to take gastric mucosal biopsy tissue samples for H.pylori culture; (4) Patients with a history of at least one failed H. pylori eradication treatment and willing to cooperate with the doctor to conduct a follow-up investigation of the eradication effect.
Exclusion criteria
Exclusion criteria: (1) Allergy or contraindication to the drugs used in the study regimen; (2) A history of gastric surgery; (3) The use of PPIs, antibiotics or steroid drugs can't be discontinued during the study; (4) Pregnancy or lactation; (5) Acute infection of mononucleosis; (6) Severe concomitant diseases such as cardiac, hepatic, renal or pulmonary dysfunction; (7) Treatment with a PPI, bismuth, or an antibiotic within 4 weeks before the study treatment; (8) Patients diagnosed or suspected to have upper gastrointestinal malignancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse Events;Helicobacter pylori drug sensitive; | — |
Countries
China
Contacts
Public ContactXiaoyong Wang
The Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University
Outcome results
None listed