Early stage lung cancer
Conditions
Interventions
1:Closed insufflation technique
2:Dilatation and collapse technique
Sponsors
Second Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients voluntarily join and sign a written informed consent; 2. The age of the subjects is 18-75 years old, regardless of gender; 3. The ECOG PS was 0 or 1; 4. Three-dimensional visualization was performed before surgery, and the surgeon judged that the tumor could be completely removed by segmentectomy, and surgical margin was expected to be greater than 2cm or the maximum diameter of the nodule; 5. Thin-slice CT suggests any of the following: ? The diameter of pulmonary nodules is 2-3cm and the consolidation-tumor ratio (CTR) is less than 0.25; ? Pulmonary nodule diameter =2cm and 0.25 < CTR < 0.5; ? Non-peripheral pulmonary nodule diameter =2cm and CTR=0.25; 6. cN0 and no distant metastasis; 7. Intraoperative freezing examination or postoperative paraffin examination suggest early lung adenocarcinoma; 8. Intraoperative freezing disease of station 12 lymph nodes showed no cancer metastasis; 9. Preoperative anesthesia risk assessment: American Society of Anesthesiologists (ASA) Level I-III; 10. Has no history of lung resection; 11. Has not received anti-tumor therapy such as radiotherapy, chemotherapy, targeted therapy and immunotherapy.
Exclusion criteria
Exclusion criteria: 1. The subject did not understand the study protocol, did not cooperate or refused to sign the informed consent; 2. The subject has a history of malignant tumor or has previously received anti-tumor therapy; 3. 3D visualization was not received before surgery; 4. The surgeon judged that segmentectomy could not ensure complete resection of the tumor; 5. has a history of lung resection, or chest trauma or surgery on the affected side of chest cavity; 6. Extensive intraoperative dense thoracic adhesion; 7. Conversion to thoracotomy; 8. Intraoperative frozen examination of intrapulmonary lymph nodes indicated cancer metastasis; 9. Pulmonary nodules are located in the right middle lung; 10. Suffered from chronic bronchitis, emphysema, asthma and other chronic lung diseases; 11. Other conditions unsuitable for inclusion in this study deemed by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intersegmental plane clarity grading;Time of operation for segmentectomy;Postoperative pulmonary function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Minimum distance between the nodule and each margin;The estimated amount of blood loss during the operation;Postoperative days for thoracic drainage;Postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactLiu WenLiang
Department of Thoracic Surgery, Second Xiangya Hospital of Central South University
Outcome results
None listed