gastric cancer,colorectal cancer
Conditions
Interventions
Group L:Intravenous lidocaine infusion before induction of anesthesia and intraoperatively
Group C:Intravenous saline infusion before induction of anesthesia and intraoperatively
Sponsors
Xuzhou Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Age = 18 years;2. ASA grade I ~ III;3. BMI:18.5-30kg/m^2;4.Patients scheduled for laparoscopic radical surgery for colorectal or gastric cancer under general anesthesia;5. Voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1.Poor preoperative comprehension, psychiatric disorders, or central nervous system disorders;2.Severe renal or hepatic insufficiency ;3.History of previous heart disease ;4.Preoperative radiation or chemotherapy;5.Preoperative use of NSAIDs;6.History of chronic pain or history of daily analgesic use;7.Allergy to lidocaine or other anesthetic drugs;8.Other conditions where the researcher deems it inappropriate to participate in this clinical study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Christensen’s Visual Analogue Scales ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual analogue scale;IL-6;TNF-a;Consumption of introperative sedative and analgesic drugs;Dosage of relief analgesics;time to the first anal exhaust, and defecation;hospital stay;postoperative tumor recurrence and metastasis; | — |
Countries
China
Contacts
Public ContactWang Liwei
Xuzhou Central Hospital
Outcome results
None listed