functional constipation
Conditions
Interventions
Experimental group:For eight weeks, patients took a daily bag of probiotics which containing 9logCFU units of probiotics.
Control group:For eight weeks, the patients took a daily bag of placebo powder, each containing no probiotics and the rest of the same ingredients.
Sponsors
Deyang City People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Meeting the diagnostic criteria of functional constipation in Rome IV standard.
Exclusion criteria
Exclusion criteria: 1. Non-Roman IV functional constipation; 2. Aged 60 years old; 3. Patients diagnosed with refractory constipation; (Patients with disease course of more than 1 year who have failed basic treatment and laxative therapy); 4. Consider secondary constipation caused by neurological diseases, metabolic diseases, obstructive diseases and drugs; 5. May be combined with mental disorders; 6. Patients with diseases related to immune deficiency or who have used immunosuppressants, serious diseases of the heart, brain, kidney and other systems, intestinal malignancies, intestinal perforation, intestinal obstruction, intestinal bleeding, etc.; 7. People who are currently taking antibiotics or have taken antibiotics in the past 4 weeks; 8. Those who have participated in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assessment of Constipation Symptoms and Types; | — |
Secondary
| Measure | Time frame |
|---|---|
| Depression Situation;Intestinal microbiota spectrum;Vaginal microbiota spectrum;Biomarkers for Constipation (Serum concentrations of excitatory neurotransmitters);Pelvic floor muscle group testing;Balloon ejection test; | — |
Countries
China
Contacts
Public ContactZheng Fan
Deyang People's Hospital
Outcome results
None listed