intermittent exotropia combined with myopia
Conditions
Interventions
0.01% atropine group:0.01% low concentration atropine eye drops once every night
0.02% atropine group:0.02% low concentration atropine eye drops once every night
0.04% atropine group:0.04% low concentration atropine eye drops once every night
Sponsors
The First Affiliated Hospital with Nanjing Medical University
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1) between 6-12 years of age; 2) basic type of intermittent exotropia (IXT); 3) having myopic refraction (spherical equivalent, SE) by cycloplegic autorefraction = -0.5 diopters (D) and >-6 D in both eyes; 4) having a best-corrected distance visual acuity (BCVA) of = 0.2 logarithms of the minimum angle of resolution (logMAR) (i.e., Snellen 20/32 or better) in each eye as measured using an Early Treatment for Diabetic Retinopathy Study (ETDRS) chart.
Exclusion criteria
Exclusion criteria: (1) diagnosed of ocular diseases or having clinically significant abnormal findings in the ocular examinations; (2) having intraocular pressure (IOP) > 21 mmHg in either eye; (3) having astigmatism by cycloplegic autorefraction = 2 D in either eye; (4) with serious health problems or cognitive disability affecting follow-up or failure to cooperate with examinations; (5) participating in other interventional trials; (6) have received any myopia control in the past 6 months, including orthokeratology, atropine eye drops, defocusing lenses and other myopia control methods; (7) allergic to atropine; (8) with peripheral anterior chamber depth < 1/3 corneal thickness;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| refraction diopter;axial length;stereoacuity;office-based control scales;deterioration rate;exodeviation magnitude; | — |
Secondary
| Measure | Time frame |
|---|---|
| pupil diameter;accommodative amplitude ;accommodative convergence/accommodation;Choroid related indicators;peripheral refraction;higher-order aberrations;near point of convergence;dry eye related indicators;corneal endothelium; | — |
Countries
China
Contacts
Public ContactLiu Hu
The First Affiliated Hospital with Nanjing Medical University
Outcome results
None listed