Study on the efficacy and safety of ultra early hyperbaric oxygen therapy for brain edema after severe traumatic brain injury

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300075305

Enrollment

Unknown

Registered

2023-08-31

Start date

2023-09-01

Completion date

Unknown

Last updated

2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Traumatic brain injury

Interventions

research group:ultra early hyperbaric oxygen therapy

Control group:None

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: It met the diagnostic criteria for severe craniocerebral injury in Neurosurgery and was confirmed by MRI and CT. Have a clear history of trauma; Patients with 3 points < Glasgow coma scale (GCS) score =8 points at admission; Admission to hospital within 6 hours after injury; He remained in a deep coma for more than 12 hours after treatment.

Exclusion criteria

Exclusion criteria: Patients with open injury, severe brain stem injury or brain death; Patients with other severe primary organ dysfunction; Patients with coagulation dysfunction; Patients with recurrent seizures; Combined with untreated pneumothorax or bulla.;those with pre-existing limb paralysis.

Design outcomes

Primary

Measure	Time frame
GCS;Cerebral edema area;	—

Countries

China

Contacts

Public ContactXiao-ting Fan

Linyi People’s Hospital

15215396929@163.com+86 152 1539 6929

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026