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Identifcation of blood-based key biomarker and immune infltration in acute pancreatitis by comprehensive bioinformatics analysis and a cohort validatio

Identifcation of blood-based key biomarker and immune infltration in acute pancreatitis by comprehensive bioinformatics analysis and a cohort validatio

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300075290
Enrollment
Unknown
Registered
2023-08-31
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Pancreatitis

Interventions

Non-acute pancreatitis group:Nil

Sponsors

First Aid Center of Affiliated Hospital of Xuzhou Medical University, Jiangsu Province
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ( 1 ) Age = 18 years ; ( 2 ) Consistent with the diagnosis of acute pancreatitis : There are two of the three diagnostic criteria : ( I ) Abdominal pain consistent with AP, ( II ) Serum lipase or amylase levels higher than three times the upper limit of normal ; ( III ) Abdominal imaging characteristic findings. ( 3 ) Obtaining informed consent ;

Exclusion criteria

Exclusion criteria: ( 1 ) Chronic pancreatitis ; ( 2 ) Patients with severe dysfunction of heart, brain, liver and kidney ; ( 3 ) Patients with autoimmune diseases or long-term use of hormone drugs ; ( 4 ) Patients with malignant tumors ; ( 5 ) With other acute or chronic inflammation or infection.

Design outcomes

Primary

MeasureTime frame
mRNA;Amylase;Triglyceride;Lipase;Acute Physiology and Chronic Health Evaluation scoring;Bedside index for severity in acutepancreatitis scoring;Modified CT severity index(MCTSI);Marshall(system organ failure)scoring;

Countries

China

Contacts

Public ContactYan Xianliang

First Aid Center of Affiliated Hospital of Xuzhou Medical University, Jiangsu Province

docyxl@163.com+86 189 5215 9710

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026