Effect of ultrasound-guided stellate ganglion block on early postoperative cognitive function of elderly gastrointestinal surgery patients

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300075264

Enrollment

Unknown

Registered

2023-08-31

Start date

2023-08-31

Completion date

Unknown

Last updated

2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cognitive disfunction

Interventions

Stellate ganglion block group:Use 0.2% ropicaine 4ml to block the right stellate ganglion

Physiological saline group:4ml saline for right stellate ganglion block operation

Eligibility

Sex/Gender

All

Age

65 Years to 100 Years

Inclusion criteria

Inclusion criteria: (1) Age = 65 years old; (2) ASA I-III ; (3) Preoperative MoCA score = 26; (4) Preoperative MMSE score > 23 ; (5) The operation is expected to last more than two hours; (6) Patients to undergo laparoscopic gastrointestinal surgery

Exclusion criteria

Exclusion criteria: (1) Obvious neurological, mental system diseases, and neurodegenerative diseases; (2) Liver and renal disfunction (ChildePugh grade C, blood creatinine > 125 µmol/L); (3) Recent use of sedative hypnotics, analgesics, antidepressants, glucocorticoids or other immunosuppressants (4) Have a history of drug and alcohol abuse; (5) Severe visual and auditory disorders affect communication; (6) BMI > 30kg/m2; (7) Patients with stellate ganglion block failure and contraindications

Design outcomes

Primary

Measure	Time frame
MMSE;MoCA;	—

Secondary

Measure	Time frame
IL-6;malondialdehyde, MDA;superoxide dismutase, SOD;	—

Countries

China

Contacts

Public ContactSun Defeng

Department of the First Affiliated Hospital of Dalian Medical University

sdf-yl@163.com+86 180 9887 6191

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026