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Understanding the Effect of Acupuncture on Nausea and Vomiting during Pregnancy from A Metabolic Perspective: A Single-Blinded Randomized, Controlled Trial

Understanding the Effect of Acupuncture on Nausea and Vomiting during Pregnancy from A Metabolic Perspective: A Single-Blinded Randomized, Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075259
Enrollment
Unknown
Registered
2023-08-31
Start date
2023-08-31
Completion date
Unknown
Last updated
2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nausea and vomiting during pregnancy

Interventions

Acupuncture :PC6, PC5, ST36, ST40, GB20, CV17, CV12 and DU20 were selected as acupoints. Auricular acupoints included CO4, CO15, TF4 and AH6a. Patients in a supine position will be needled after routi
Sham Acupuncture:The sACP group will undergo acupuncture with nonpenetrative acupuncture at nonacupuncture points. The nonmeridional points, which are the points 5 to 10 mm away from the acupoints in

Sponsors

Assisted Reproduction Unit, Department of Obstetrics and Gynecology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: ?Presented with fatigue, loss of appetite, nausea and vomiting.?age 18-40 years. ?Gynecological b-ultrasound confirmed intrauterine pregnancy with gestational ages of 5-11 weeks. ?pregnancies conceived via assisted reproductive technologies. ?Participants voluntarily participated in the study and signed informed consent.

Exclusion criteria

Exclusion criteria: ?Ectopic pregnancy. ?Patients with abnormal thyroid function, abnormal renal function, severe cardiovascular or cerebrovascular diseases, or tumors. ?Patients with severe gastrointestinal disorders, such as gastrointestinal bleeding, gastrointestinal perforation, inflammatory bowel disease, peptic ulcers, hepatitis, and liver cirrhosis. ?Patients received any medication for one month prior to this study. ?Known or suspected halo acupuncture. ?Patients with broken skin or ulceration.

Design outcomes

Primary

MeasureTime frame
pregnancy-unique quantification of emesis,PUQE;

Secondary

MeasureTime frame
serum HCG;uchal translucency (NT) thickness;live birth rate;preterm birth rarte;Nontargeted metabolomics;

Countries

China

Contacts

Public ContactSongying Zhang

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine

zhangsongying@zju.edu.cn+86 138 0572 7588

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026