Respiratory failure occurred after extubation
Conditions
Interventions
Group 1:Orderly setting velocity of 40L/min,30L/min,50L/min, 40L/min
Group 2:Orderly setting velocity of 40L/min,50L/min,30L/min, 40L/min
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Patients were planning to undergo extubation and had one or more of the following high-risk factors for reintubation: (1) age>65 years old;(2) Heart failure was the cause of intubation;(3) moderate to severe chronic obstructive pulmonary disease;(4) APACHE II score on the day of extubation >12.(5) BMI>30 kg/m2;(6) airway obstruction;(7) poor ability to clear airway secretions;(8) difficult or delayed offline;(9) two or more pulmonary or cardiac or renal complications;(10) duration of mechanical ventilation more than 7 days.
Exclusion criteria
Exclusion criteria: (1) age< 18 years old;(2) hemodynamic instability (hypotension, mean arterial pressure <60 mmHg despite adequate blood volume and use of vasoactive agents);(3) evidence of pneumothorax on chest X-ray or computed tomography;(4) contraindications to electrical impedance tomography (EIT) (e.g., patients with implantable defibrillator);(5) inability to place an EIT electrode band (e.g., effect of wound dressing or thoracic drainage tube);(6) patients with tracheotomy;(7) patients who did not consent to participate in the study;(8) Other study protocols were enrolled.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Distribution of gas; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung injury markers;Blood gas analysis; | — |
Countries
China
Contacts
Public ContactLiu Xiaoqing
The First Affiliated Hospital of Guangzhou Medical University
Outcome results
None listed