Median effective dose of cyclopofol combined with sufentanil for inhibiting tracheal intubation response in elderly patients

Median effective dose of ciprofol combined with sufentanil for inhibiting tracheal intubation response in elderly patients

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2300075223

Enrollment

Unknown

Registered

2023-08-30

Start date

2023-08-31

Completion date

Unknown

Last updated

2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General anesthesia tracheal intubation in elderly patients

Interventions

Group P:Propofol 1.6 mg/kg, the dosage of propofol administered to the next patient is determined by whether the previous patient experienced tracheal intubation reactions.

Group C:Cyclopol 0.3 mg/kg, the dosage of cyclopol administered to the next patient is determined by whether the previous patient experienced tracheal intubation reactions.

Eligibility

Sex/Gender

All

Age

65 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age =65 years, BMI of 18 - 20 kg/m2, ASA I-II

Exclusion criteria

Exclusion criteria: HR=100 beats/min or SBP=160mmHg or MAP=120mmHg at rest after entering the room; Severe cardiopulmonary dysfunction; severe liver and kidney function injury; Allergy to related drugs; history of abuse of sedative or narcotic drugs; Keywords cognitive dysfunction; complex difficult airway indication; Tracheal intubation times>1 time.

Design outcomes

Primary

Measure	Time frame
median effective dose;	—

Secondary

Measure	Time frame
Tracheal intubation reaction;	—

Countries

China

Contacts

Public ContactXu Hai

the Second Hospital of Jiaxing

xhjxey@163.com+86 159 8837 5602

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026