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Correlation of ApoE-regulated lipid reorganisation with pathological processes in Parkinson's disease

Correlation of ApoE-regulated lipid reorganisation with pathological processes in Parkinson's disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2300075210
Enrollment
Unknown
Registered
2023-08-29
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson‘s disease

Interventions

PD :NA
Control:NA

Sponsors

Nanfang Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) voluntarily signed informed consent; (2) aged >18 and <80years; (3) in accordance with the Clinical Diagnostic Criteria for Movement Disorder Diseases (2015).

Exclusion criteria

Exclusion criteria: (1) patients with pulmonary, renal, cardiac, hepatic and other organ dysfunctions; (2) conditions such as eating disorders, malnutrition, endocrinology, malignancy, chronic blood loss (fecal occult blood negative), haematological disorders, and other conditions that may affect the results of the haematology study; (3) patients who are illiterate, deaf, or other patients who may be affected in the clinical assessment due to communication barriers; (4)Patients with diabetes or taking lipid-lowering drugs; (5)patients who are not considered suitable for participation in this study in the judgement of the investigator.

Design outcomes

Secondary

MeasureTime frame
blood lipid level;routine blood test;UPDRS 3.0;Non-motor symptom scores;Disease progression;

Primary

MeasureTime frame
lipid profile;Oligomerization and phosphorylation of erythrocyte membrane alpha-Synuclein;

Countries

China

Contacts

Public ContactXu Yunqi

Nanfang Hospital of Southern Medical University

xyqtf@smu.edu.cn+86 137 5183 8377

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026