Mild cognitive impairment, MCI
Conditions
Interventions
Intervention group:On the basis of control group, risk identification intervention and targeted program were adopted
Control group:Health education
Sponsors
Nanjing University of Chinese Medicine; Nanjing Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Age 60~80 years old; (2) years of education =6 years; (3) mini-mental state examination (MMSE)=24 points; (4) Montreal Cognitive Assessment Scale (MoCA) score < 26 points, if the years of education =12 years, score plus 1 point; (5) The Clinical Dementia Rating Scale (CDR) score was 0.5, excluding dementia patients; (6) The Auditory verb learn test-Huashan version (AVLT-H) score is less than 1.5 standard deviations lower than the normal control. (7) Activities of daily living (ADL) score =23 points; (8) normal visual hearing, able to conduct neuropsychological tests; (9) Voluntary participation and signing of informed consent.
Exclusion criteria
Exclusion criteria: (1) Diagnosis of Alzheimer's disease or other types of dementia. (2) Patients with a history of cerebrovascular disease, including ischemic cerebrovascular disease, hemorrhagic cerebrovascular disease, and neurological diseases such as hemiplegia and aphasia. (3) Patients with secondary metabolic disorders caused by certain endocrine, genetic and nervous system diseases, and patients with metabolic diseases caused by drugs. (4) Critically ill patients, patients with other central nervous system injury diseases or history, such as brain trauma, encephalitis, epilepsy, tumors, infections, severe liver and kidney dysfunction, blood system diseases, central nervous system demyelinating diseases, central nervous system degenerative diseases, etc. (5) have received treatment to improve cognitive function in the past 3 months, or are participating in other clinical trials; (6) Patients with cardiac pacemakers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cognitive function; | — |
Secondary
| Measure | Time frame |
|---|---|
| sleep quality;quality of life; | — |
Countries
China
Contacts
Public ContactYamei Bai;Xiujun Guo
Nanjing University of Chinese Medicine; Nanjing Hospital of Traditional Chinese Medicine
Outcome results
None listed