digestive tract disease
Conditions
Interventions
Propofol1:Propofol 1mg/kg + Esketamine
Propofol 2:Propofol 2mg/kg + Esketamine
Propofol 3:Propofol 3mg/kg + Esketamine
Propofol 4:Propofol 4mg/kg + Esketamine
Sponsors
XuZhou Children's Hospital
Eligibility
Sex/Gender
All
Age
6 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1) Aged 3~12 years; 2) Due to dyspepsia, gastric ulcer, or other diseases need to undergo upper gastrointestinal endoscopy; 3) ASA score is I or II.
Exclusion criteria
Exclusion criteria: 1) Patients with contraindications to general anesthesia; 2) Patients who are tolerant or allergic to esketamine hydrochloride or propofol; 3) Children who are prescribed medications before anesthesia; 4) Past coagulation abnormalities and bleeding tendency; 5) Abnormal liver or kidney function or history of liver or kidney disease; 6) The investigator considers it inappropriate to participate; 7) The child or parents refuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reaction when entering the endoscop; | — |
Secondary
| Measure | Time frame |
|---|---|
| examination time;awakening time;gastroenterologist's satisfaction;patient's satisfaction;heart rate;pulse oxygen saturation;mean blood pressure; | — |
Countries
China
Contacts
Public ContactKeqing Niu
XuZhou Children's Hospital
Outcome results
None listed