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The clinical study of 16S rDNA sequencing to analyze the characteristics of intestinal and pus cavity flora of perianal abscess and the effect of Yu-Nong formula on postoperative prognosis of perianal abscess

The clinical study of 16S rDNA sequencing to analyze the characteristics of intestinal and pus cavity flora of perianal abscess and the effect of Yu-Nong formula on postoperative prognosis of perianal abscess

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2300075172
Enrollment
Unknown
Registered
2023-08-28
Start date
2023-09-01
Completion date
Unknown
Last updated
2023-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perianal abscess

Interventions

Treatment Group:Stool samples were collected before operation. The operation was performed by incision and drainage of perianal abscess under spinal anesthesia. The operation was performed by associat
Control Group:No oral medication was given to the control group,just given 1:10,000 diluted potassium permanganate solution for 2 weeks.
Healthy control group:NA

Sponsors

Yangzhong People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1 surgical patients with perianal abscess. 2 between the ages of 18 and 70. 3 no serious basic disease, male or female. 4 participants voluntarily participated and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1 suffering from mental diseases, mental disorders, cardiovascular diseases, malignant tumors, etc. . 2 allergic constitution, abnormal function of liver and kidney, abnormal coagulation function, pregnant and lactating women, etc. . (3) severe underlying diseases such as diabetes with inflammatory bowel disease, tuberculosis and poorly controlled blood glucose. 4 patients who had been treated with antibiotics or oral probiotics 4 weeks before enrollment. 5 poor compliance, unable to complete the follow-up.

Design outcomes

Secondary

MeasureTime frame
Healing time;Safety indicator;TCM syndrome integral;Wound secretions;

Primary

MeasureTime frame
16S rDNA sequencing was used to analyze the flora characteristics;Recurrence rate;

Countries

China

Contacts

Public Contactshanzhong chen

Yangzhong People's Hospital

284718789@qq.com+86 182 4887 9466

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026