Inflammatory Bowel Disease
Conditions
Interventions
Sponsors
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Colonic Crohn's Disease Active/Remission Group: 1)Age 18-70 years; 2)Confirmed diagnosis of colonic Crohn's disease for at least 3 months with histological evidence; 3)Simplified Crohn's Disease Activity Index (CDAI) > 4 during the active phase of CD; 4)Simplified Crohn's Disease Activity Index (CDAI) = 4 during the remission phase of CD; 5)Signed informed consent form; Ulcerative Colitis Active/Remission Group: 1)Age 18-70 years; 2)Confirmed diagnosis of ulcerative colitis for at least 3 months with histological evidence; 3)Endoscopic Mayo score of 2-3 during the active phase of UC; 4)Endoscopic Mayo score of 0-1 during the remission phase of UC; 5)Signed informed consent form; Normal Control Group: 1)Age 18-70 years; 2)Patients without a diagnosis of IBS or IBD; 3)No history of underlying gastrointestinal diseases; 4)No recent intestinal infections in the past two weeks; 5)Normal colonoscopy findings; 6)Signed informed consent form.
Exclusion criteria
Exclusion criteria: 1)History of gastrointestinal surgery; 2)Pregnant or planning to become pregnant; 3)Undifferentiated inflammatory bowel disease; 4)Coexisting colonic malignancy; 5)Presence of infectious colitis or diverticulitis; 6)Patients with any psychiatric disorders or individuals unable to cooperate with this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wall thickness; | — |
Secondary
| Measure | Time frame |
|---|---|
| White blood cell count;Hemoglobin;Platelet;C-reactive protein;Erythrocyte Sedimentation Rate;Albumin;Fecal calprotectin;Endoscopic score; | — |
Countries
China
Contacts
Public ContactZhou Fan
Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School
Outcome results
None listed