Assisted diagnosis of gastric cancer
Conditions
Interventions
Gold Standard:At present, the common clinical methods of gastric cancer diagnosis gastroscopy and/or histopathological examination are also the gold standard for clinical gastric cancer diagnosispermi
Index test:Biomarker: DNA methylation test of Reprimo and CABIN1 gene in blood cell-free DNA .
Sponsors
Drum Tower Hospital Affiliated to Nanjing University School of Medicine
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Fully competent, 40~75 years old, regardless of gender; 2) Meet the characteristics of the target population of this trial, including gastric cancer, suspected gastric cancer, benign gastric disease, other cross-cancers or diseases, etc.; 3) Be willing to provide blood samples; 4) Willing to provide clinical diagnosis report and conclusion; 5) Agree to participate in this clinical trial and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) Have received any form of oncology treatment before enrollment, including medication, chemotherapy, radiotherapy, surgery, biology Treat; 2) Inability to provide blood samples for subjective or objective reasons; 3) Refusal to use tissue biopsy samples and/or postoperative samples for histopathological examination; 4) Subjects who are not suitable to participate in this trial after full discussion by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reprimo and CABIN1 gene methylation assays;Accuracy ;Sensitivity ;Specificity ; | — |
Countries
China
Contacts
Public ContactXiaoping Zou
The Affiliated Hospital of Nanjing University Medical School
Outcome results
None listed